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The online tutorial series with a case reinforces practical 
application of tools and competencies acquired during the 
live activity. Each tool is a combination of essentials in 
clinical practice, links to relevant scientific publications, and 
printable handout material for reference. Clinical Case 
following the online tutorials gives the learners an opportunity 
to earn extra CE credit upon completion. 
 
 
Differentiating Types of PainAssessment of Pain Know Your Drugs: Non-Opioids Know Your Drugs: Opioids Minimizing Adverse EffectsClinical Case  
 
 
 
What other changes would you consider for this patient?
In addition to discontinuing tramadol and methadone due to concerns regarding QT 
interval prolongation, the clinician may consider weaning and eventually discontinuing 
cyclobenzaprine and carisoprodol as these may not be optimal choices for Emily's type 
of pain and can be contributing to adverse effects (such as memory loss). An SNRI (such 
as venlafaxine, milnacipran, or duloxetine) should be considered to treat fibromyalgia 
in addition to optimizing the dose of pregabalin. A controlled-release opioid can be 
used in place of methadone while topical diclofenac can be effective to treat knee 
and shoulder pain. This multimodal approach may offer Emily better results in 
alleviating her pain.5,6  Physical therapy and weight loss should also be encouraged 
to complement her pharmacotherapy program.
The currently available long-acting oral opioid formulations are listed here: 
			
			
			| Name | Dosing Interval | Administration |  
			| Kadian (morphine) 
 | q12h or q24h | Capsule, sprinkle, G-tube |  
			| Avinza (morphine) 
 | q24h | Capsule, sprinkle |  
			| OxyContin (oxycodone) 
 | q8-12h | Tablet |  
			| MS Contin (morphine) 
 | q8h or q12h | Tablet |  
			| Opana ER (oxymorphone) 
 | q12h | Tablet |  
			| Exalgo (hydromorphone) 
 | q24h | Tablet |  
			| Nucynta ER (tapentadol) 
 | q12h | Tablet |  
Does Emily present with any risk factors for opioid abuse or misuse? 
 
 
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