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About Initiative
Accreditation Faculty Workshops Point of Care Webcast on Demand  Live webcast Outcomes Jointly sponsored by University of Kentucky College of Pharmacy and Vemco MedEd  This activity is supported by an educational grant from Janssen Pharmaceuticals, Inc., administered by Janssen Scientific Affairs, LLC 
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The online tutorial series with a case reinforces practical
application of tools and competencies acquired during the
live activity. Each tool is a combination of essentials in
clinical practice, links to relevant scientific publications, and
printable handout material for reference. Clinical Case
following the online tutorials gives the learners an opportunity
to earn extra CE credit upon completion.
Which of her current medications would concern you most regarding Emily's QTc prolongation? Many drugs are known to prolong the QT interval and/or increase the risk for torsades de pointes that may generate into ventricular fibrillation. In this patient, trazodone and methadone are both known to prolong the QT interval. Since the EKG revealed some QTc prolongation, the clinician should consider weaning or discontinuing these medications immediately. Methadone monitoring recommendations suggest that all patients be screened prior to initiation of treatment with a pre-treatment EKG to measure QTc interval and have a follow-up EKG within 30 days and annually thereafter.1 An additional EKG is recommended for all patients if the methadone dose exceeds 100 mg/day or if the patient experiences unexplained syncope and seizures.1 Would you consider adding an NSAID for Emily? |
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