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The Baddest Bug on the Ward: An Ongoing Debate

Medium: Vodcast (Online Activity with RSS Feed)
Release Date: Tuesday, December 8, 2009
Credit Expiration Date: Friday, April 29, 2011

Credit Hours
Pharmacists CPE: 2.0 (0.2 CEUs)

Activity Overview
This online activity is based on the proceedings of a continuing education symposium held on December 8, 2009, during the 44th ASHP Midyear Clinical Meeting and Exhibition in Las Vegas, Nevada.

This Vodcast (audio with accompanying slides) has 3 episodes which will be released monthly beginning February 1, 2010.

  • Episode 1: MRSA
  • Episode 2: ESBL/KPC-producing Enterobacteriaceae
  • Episode 3: Acinetobacter and Pseudomonas
Each episode begins with a presentation of why the particular pathogen is among the most challenging in the hospital setting. This is followed by a presentation of tactics that clinical pharmacists can use to appropriately manage infections due to that pathogen. The challenges associated with such infections are further discussed from the clinical, infection control, and microbiology perspectives.

Note: If you have received credit by attending the live symposium by the same name, you are not eligible to apply for credit for this online version.

Practice Gap and Educational Need
According to the Centers for Disease Control and Prevention, approximately two million people develop bacterial infections in US hospitals each year, resulting in nearly 100,000 deaths. In 2004, the Infectious Diseases Society of America (IDSA) published the call-to-action “Bad Bugs, No Drugs” that highlighted the problem of antimicrobial resistance and the lack of new agents in development. This has since been updated to “Bad Bugs, No ESKAPE”, where the IDSA identified the most problematic pathogens that are able to “escape” the effects of currently available agents. These pathogens include methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumannii, and Pseudomonas aeruginosa, and ESBL-producing and KPC-producing Enterobacteriaceae.

The lack of new antimicrobial agents limits the clinicians’ ability to effectively treat hospital-acquired infections caused by these difficult pathogens. Therefore, it is necessary to recognize the challenges associated with each type of infection and how to address them in the clinical setting. Positive clinical outcomes can be achieved through continued education on appropriate use of antimicrobial agents.

Target Audience
This activity has been designed to meet the needs of pharmacists who are responsible for the management of serious infections in hospitalized patients.

Learning Objectives
Those healthcare professionals participating in this knowledge-based activity will be able at its conclusion to:

  • Identify the characteristics of key multidrug-resistant bacteria that cause hospital-acquired infections (HAIs).
  • Implement antimicrobial dosing based on pharmacokinetic and pharmacodynamic principles to reduce resistance development.
  • Proactively contribute as a key decision-maker in the management of patients with HAIs.

Faculty
Richard H. Drew, PharmD, MS, BCPS
Professor, Campbell University School of Pharmacy and Health Sciences
Associate Professor of Medicine (Infectious Diseases)
Duke University School of Medicine
Durham, North Carolina

Loren G. Miller, MD, MPH
Associate Professor of Medicine,
David Geffen School of Medicine at UCLA
Division of Infectious Diseases
Director, Infection Control Program
Harbor-UCLA Medical Center
Torrance, California

David P. Nicolau, PharmD, FCCP, FIDSA
Director, Center for Anti-Infective Research and Development
Hartford Hospital
Hartford, Connecticut

Robert P. Rapp, PharmD, FCCP
Professor of Pharmacy Emeritus, College of Pharmacy
Professor of Surgery Emeritus, College of Medicine
University of Kentucky Medical Center
Lexington, Kentucky

George G. Zhanel, PharmD, PhD
Professor
Department of Medical Microbiology and Infectious Diseases
Faculty of Medicine
University of Manitoba
Winnipeg, Canada

Accreditation
Pharmacists
Accreditation Council for Pharmacy Education Massachusetts College of Pharmacy and Health Sciences (MCPHS) is accredited by the Accreditation Council for Pharmacy Education as a provider for continuing pharmacy education. Participants will receive 2.0 contact hours (0.2 CEUs) for this activity. No partial credit will be awarded.

ACPE UAN: 0026-9999-09-083-H01-P
Activity type: Knowledge-based

For questions regarding the accreditation of this activity, please contact MCPHS at Kristin.Reitz@mcphs.edu

Method of Participation and Instruction for Credit

  1. Review the entire CE information including target audience, learning objectives, and disclosures.
  2. Review all three episodes in their entirety.
  3. Print and complete the Post Test, Evaluation, and Credit Application form.
  4. Mail the completed Post Test, Evaluation, and Credit Application form to Vemco MedEd, 245 US Highway 22, Suite 304, Bridgewater, NJ 08807 or fax to (908) 235-4222.
  5. Post Test, Evaluation, and Credit Application Form will be available after the release of Episode 3.
  6. Please note that you have to receive a score of at least 70% on the Post Test to receive credit
Documentation of credit will be mailed within 4 weeks of receipt of the completed Post Test, Evaluation, and Credit Application form.

Disclosure of Conflicts of Interest
Massachusetts College of Pharmacy and Health Sciences and Vemco MedEd require faculty, planners, and others who are in a position to control the content of continuing education activities to disclose to the audience any real or apparent conflict of interest related to the activity. All identified conflicts of interest are reviewed to ensure fair balance, objectivity, and scientific rigor in all activities. The faculty is further required to disclose discussion of off-label uses in their presentations.

Disclosure
Faculty
Richard H. Drew, PharmD, MS, BCPS serves on the advisory boards for Schering-Plough, Wyeth-Ayerst, and Astellas. He receives research support from Schering-Plough and Cubist. He serves on speakers bureaus for Schering-Plough, Wyeth-Ayerst, and Merck and is on the development Team for CustomID.

Loren G. Miller, MD, MPH is a consultant for Theravance and receives research/grant support from Pfizer and Cubist.

David P. Nicolau, PharmD, FCCP, FIDSA serves on the advisory boards and is a consultant for AstraZeneca, Cubist, Wyeth, Pfizer, Ortho-McNeil, and Merck. He receives grant/research support, has intellectual property/patents and serves on speakers bureaus for AstraZeneca, Ortho-McNeil, Cubist, Wyeth, Merck, and Pfizer.

Robert P. Rapp, PharmD, FCCP serves on the advisory boards for Pfizer, Ortho-McNeil, and Astellas. He serves on the speakers bureaus for Pfizer, Ortho-McNeil, and Astellas.

George G. Zhanel, PharmD, PhD serves on the advisory boards for Merck, Ortho-McNeil, and Wyeth. He receives research/grant support from Abbott, Affinium, Astellas, Wyeth, Pfizer, TaiGen, Ortho-McNeil, Bayer, Sepracor, and Advanced Life Sciences.

Planning Committee Members
Employees of Vemco MedEd and Massachusetts College of Pharmacy and Health Sciences have no relevant financial relationships to disclose.

Disclosure Off-label Use
The following off-label uses of antimicrobial agents will be discussed during this activity: dalbavancin, oritavancin, iclaprim, ceftobiprole and ceftaroline for the treatment of MRSA infections; tigecycline for the treatment of hospital-acquired pneumonia and A. baumannii infections; telavancin for the treatment of hospital-acquired pneumonia; meropenem for the treatment of cystic fibrosis and administered via a 3-hour infusion; doripenem for the treatment of nosocomial pneumonia and cystic fibrosis.

Joint Sponsorship
This activity is jointly sponsored by Massachusetts College of Pharmacy and Health Sciences and Vemco MedEd.

Commercial Support
This activity is supported by an educational grant from Ortho-McNeil, Inc., administered by Ortho-McNeil Janssen Scientific Affairs, LLC.

Fee
There is no fee to participate in this educational activity.

Hardware/Software Requirements
Web Browser
Internet Explorer or Mozilla
Note: Please disable any “pop-up blocker” features.

Software
Flash Player to view the presentations
Adobe Acrobat Reader version 4 or above to view PDF files (If you do not have Acrobat Reader, you can download it for free from http://get.adobe.com/reader)

Connection Speed
Cable, DSL, or better of at least 300 kbps

Hardware
PC or Apple to view the presentations
Audio Speakers

System Check
Please e-mail any questions or concerns to info@vemcomeded.com.

Copyright Statement
Copyright © 2010 Vemco MedEd, LLC. All Rights Reserved. Permission for accreditation use granted to Massachusetts College of Pharmacy and Health Sciences.

Disclaimer
The opinions expressed in this educational activity are those of the faculty and do not reflect the views of Massachusetts College of Pharmacy and Health Sciences and Vemco MedEd. This educational activity may discuss off-label and/or investigational uses and dosages for therapeutic products/procedures that have not been approved by the United States Food and Drug Administration (FDA). Massachusetts College of Pharmacy and Health Sciences and Vemco MedEd do not recommend the use of any product/procedure outside of the labeled indications. A qualified healthcare professional should be consulted before using any therapeutic product/procedure discussed. Learners should verify all information and data before treating patients or employing any therapies described in this continuing education activity. Please refer to the official prescribing information for each product/procedure for approved indication, contraindications, and warnings.

Privacy Policy
http://www.vemcomeded.com/privacy.asp

Contact Information
For questions regarding the accreditation of this activity, please contact MCPHS at Kristin.Reitz@mcphs.edu.

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Episode 2

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Episode 3

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